New push for most in US to get at least 1 HIV test

WASHINGTON (AP) — There's a new push to make testing for the AIDS virus as common as cholesterol checks.

Americans ages 15 to 64 should get an HIV test at least once — not just people considered at high risk for the virus, an independent panel that sets screening guidelines proposed Monday.

The draft guidelines from the U.S. Preventive Services Task Force are the latest recommendations that aim to make HIV screening simply a routine part of a check-up, something a doctor can order with as little fuss as a cholesterol test or a mammogram. Since 2006, the Centers for Disease Control and Prevention also has pushed for widespread, routine HIV screening.

Yet not nearly enough people have heeded that call: Of the more than 1.1 million Americans living with HIV, nearly 1 in 5 — almost 240,000 people — don't know it. Not only is their own health at risk without treatment, they could unwittingly be spreading the virus to others.

The updated guidelines will bring this long-simmering issue before doctors and their patients again — emphasizing that public health experts agree on how important it is to test even people who don't think they're at risk, because they could be.

"It allows you to say, 'This is a recommended test that we believe everybody should have. We're not singling you out in any way,'" said task force member Dr. Douglas Owens, of Stanford University and the Veterans Affairs Palo Alto Health Care System.

And if finalized, the task force guidelines could extend the number of people eligible for an HIV screening without a copay in their doctor's office, as part of free preventive care under the Obama administration's health care law. Under the task force's previous guidelines, only people at increased risk for HIV — which includes gay and bisexual men and injecting drug users — were eligible for that no-copay screening.

There are a number of ways to get tested. If you're having blood drawn for other exams, the doctor can merely add HIV to the list, no extra pokes or swabs needed. Today's rapid tests can cost less than $20 and require just rubbing a swab over the gums, with results ready in as little as 20 minutes. Last summer, the government approved a do-it-yourself at-home version that's selling for about $40.

Free testing is available through various community programs around the country, including a CDC pilot program in drugstores in 24 cities and rural sites.

Monday's proposal also recommends:

—Testing people older and younger than 15-64 if they are at increased risk of HIV infection,

—People at very high risk for HIV infection should be tested at least annually.

—It's not clear how often to retest people at somewhat increased risk, but perhaps every three to five years.

—Women should be tested during each pregnancy, something the task force has long recommended.

The draft guidelines are open for public comment through Dec. 17.

Most of the 50,000 new HIV infections in the U.S. every year are among gay and bisexual men, followed by heterosexual black women.

"We are not doing as well in America with HIV testing as we would like," Dr. Jonathan Mermin, CDC's HIV prevention chief, said Monday.

The CDC recommends at least one routine test for everyone ages 13 to 64, starting two years younger than the task force recommended. That small difference aside, CDC data suggests fewer than half of adults under 65 have been tested.

"It can sometimes be awkward to ask your doctor for an HIV test," Mermin said — the reason making it routine during any health care encounter could help.

But even though nearly three-fourths of gay and bisexual men with undiagnosed HIV had visited some sort of health provider in the previous year, 48 percent weren't tested for HIV, a recent CDC survey found. Emergency rooms are considered a good spot to catch the undiagnosed, after their illnesses and injuries have been treated, but Mermin said only about 2 percent of ER patients known to be at increased risk were tested while there.

Mermin calls that "a tragedy. It's a missed opportunity."

___

Online:

Task force recommendation: http://www.uspreventiveservicestaskforce.org

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An ethics debate over embryos on the cheap









Dr. Ernest Zeringue was looking for a niche in the cutthroat industry of fertility treatments.


He seized on price, a huge obstacle for many patients, and in late 2010 began advertising a deal at his Davis, Calif., clinic unheard of anywhere else: Pregnancy for $9,800 or your money back.


That's about half the price for in vitro fertilization at many other clinics, which do not include money-back guarantees. Typically, insurance coverage is limited and patients pay again and again until they give birth — or give up.





Those patients use their own eggs and sperm — or carefully select donors when necessary — and the two are combined in a petri dish to create a batch of embryos. Usually one or two are then transferred to the womb. Any embryos left over are the property of the customers.


Zeringue sharply cuts costs by creating a single batch of embryos from one egg donor and one sperm donor, then divvying it up among several patients. The clinic, not the customer, controls the embryos, typically making babies for three or four patients while paying just once for the donors and the laboratory work.


People buying this option from Zeringue must accept concessions: They have no genetic connection to their children, and those children will probably have full biological siblings born to other parents.


Inside the industry, Zeringue's strategy for making embryos on the cheap has spurred debate about the ethical boundaries of creating life.


"I am horrified by the thought of this," said Andrew Vorzimer, a Los Angeles fertility lawyer alarmed that a company — not would-be parents — controls embryos. "It is nothing short of the commodification of children."


Other experts say they see no problem with the arrangement, although the business model and the issues it raises are to be discussed at a meeting in January of the ethics committee of the American Society for Reproductive Medicine.


Zeringue said the concerns are overblown.


Most of his customers have run out of money and patience by the time they come to his clinic, he said: "They're kind of at the end of the line."


::


Natosha Dukart and her husband, Brad, an oil field worker, spent more than $100,000 without producing a child. They ran up credit cards, flipped houses and moved four times to help finance round after round of IVF.


It was never clear if the problem was her eggs or his sperm.


After eight unsuccessful attempts, Natosha took to the Internet and found Zeringue's clinic, California IVF: Davis Fertility Center Inc., and its embryo program, California Conceptions. With no financial risk, there was nothing to lose.


"It was an easy choice," Natosha said.


She sent their photographs to the clinic and filled out a form saying they wanted a Caucasian baby. Two months later, they received a profile of an embryo the clinic had frozen in storage. Both donors had brown eyes and healthy family histories.


The Dukarts liked the description and this February traveled from their home near Calgary to Davis in an attempt to get Natosha pregnant.


"It was just as emotional as it was with our own embryos," she said.


Last month, at age 39, she gave birth to a healthy 7-pound girl with blue eyes and dark hair. The couple named her Milauna.





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Gaza Violence Is Unabating as Other Nations Push for Truce





GAZA CITY — Israeli forces killed at least 11 people, including several children, in a single airstrike that destroyed a home here on Sunday, as Israel pressed its bombardment of the Gaza Strip for a fifth day, deploying warplanes and naval vessels to pummel the coastal enclave.




The airstrike, which the Israeli military said was meant to kill a Palestinian militant involved in the recent rocket attacks, was the deadliest operation to date and would no doubt weigh on negotiations for a possible cease-fire. Among the dead were five women and four small children, The Associated Press reported, citing a Palestinian health official.


Two media offices were also hit on Sunday, and Prime Minister Benjamin Netanyahu of Israel warned of a “significant” expansion in the onslaught, which has already killed over 50 people, many of them civilians.


Speaking on Sunday from Bangkok, President Obama condemned missile attacks by Palestinian fighters in Gaza and defended Israel’s right to protect itself.


“There’s no country on earth that would tolerate missiles raining down on its citizens from outside its borders,” Mr. Obama said in his first public comments since the violence broke out. “We are fully supportive of Israel’s right to defend itself.”


The president also said that efforts were under way to address Israel’s security concerns and end the violence. “We’re going to have to see what kind of progress we can make in the next 24, 36, 48 hours,” Mr. Obama said.


Even as the diplomacy intensified on Sunday, the attacks continued in Gaza and Israel.


Mr. Netanyahu made his warning as militants in Gaza aimed at least one rocket at Tel Aviv, a day after Israeli forces broadened the attack beyond military targets, bombing centers of government infrastructure in Gaza, including the four-story headquarters of the Hamas prime minister.


“We are exacting a heavy price from Hamas and the terrorist organizations, and the Israel Defense Forces are prepared for a significant expansion of the operation,” Mr. Netanyahu told his cabinet at its routine Sunday meeting, referring directly to the of thousands of reservists who have been called up and the massing of armor on the Gaza border that many analysts have interpreted as preparations for a possible invasion.


“I appreciate the rapid and impressive mobilization of the reservists who have come from all over the country and turned out for the mission at hand,” Mr. Netanyahu said. “Reservist and conscript soldiers are ready for any order they might receive.”


His remarks were reported shortly after a battery of Israel’s Iron Dome defense shield, hastily deployed near Tel Aviv on Saturday in response to the threat of longer-range rockets, intercepted at least one aimed at the city on Sunday, Israeli officials said. It was the latest of several salvos that have illustrated Hamas’s ability to extend the reach of its rocket attacks.


Since Wednesday, when the escalation of the conflict began, Iron Dome has knocked 245 rockets out of the sky, the military said Saturday, while 500 have struck Israel.


The American-financed system is designed to intercept only rockets streaking toward towns and cities and to ignore those likely to strike open ground. But on Sunday a rocket fired from Gaza plowed through the roof of an apartment building in the southern Israeli city of Ashkelon. There were no immediate reports of casualties there.


In Gaza City, the crash of explosions pierced the quiet several times throughout the early morning.


Before the latest deadly strike involving civilians on Sunday, Hamas health officials had said the Palestinian death toll had risen to 53. One of the latest victims was a 52-year-old woman whose house in the eastern part of Gaza City was bombed around lunchtime.


A few hours earlier, a Hamas militant was killed and seven people were wounded in an attack on the Beach Refugee Camp, where Ismail Haniya, the Hamas prime minister, has a home. Those killed on Sunday included three children ages 1 through 5, the health officials said.


In Israel, 3 civilians have died and 63 have been injured. Four soldiers were wounded on Saturday.


The onslaught continued despite talks in Cairo that President Mohamed Morsi of Egypt said Saturday night could soon result in a cease-fire. Mr. Netanyahu said he would consider a comprehensive cease-fire if the launchings from Gaza stopped.


The attack on Mr. Haniya’s office, one of several on government installations, came a day after he hosted his Egyptian counterpart in the same building, a sign of Hamas’s new legitimacy in a radically redrawn Arab world.


Jodi Rudoren and Fares Akram reported from Gaza City. Reporting was contributed by Isabel Kershner, Carol Sutherland and Iritz Pazner Garshowitz from Jerusalem; Tyler Hicks from Gaza, Peter Baker from Bangkok, Alan Cowell from London, Michael Schwirtz from New York and David D. Kirkpatrick and Mayy El Sheikh from Cairo.



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Tom Cruise & George Clooney Sign On to Sci-Fi Films & More Casting News















11/18/2012 at 06:30 PM EST







George Clooney and Tom Cruise


Daniel Deme/EPA/Landov; Jackson Lee/Splash News Online


Get ready to squirm!

Tom Cruise, George Clooney and Ashley Greene have all signed on to star in some creepy film projects.  

Cruise takes on aliens in the sci-fi war flick All You Need Is Kill, Zimbio reports. After dying in battle, the alien-fighting soldier Cruise must relive the day again and again until he can escape the cycle. The movie is scheduled for a March 2014 release.

Meanwhile, Clooney is in talks to play the lead in 1952, a sci-fi flick about a man who contacts extra-terrestrial life on Earth, Variety reports. 

After starring in the Twilight saga, Greene is no stranger to the supernatural. She's been tapped for Satanic, a horror movie that follows a group of college students who spend Thanksgiving break in their dorm, only to battle a mysterious gang and try to survive what they thought would be a relaxing week, TheWrap reports.

Also coming soon: 

• A third season is in the works for American Horror Story, Deadline reports. Jessica Lange is one of several actors set to return in different roles for the new installment. Production will begin in summer 2013 and premiere in the fall of 2013.

• It's a family affair for Jack Nicholson and Robert Downey Jr., who will play father and son in The Judge, Ace Showbiz reports. The courtroom drama follows a lawyer who comes home after his mother's death only to discover that his father is a suspect in the murder.

• After endless rumors, Michael Bay has made it official on his website: Mark Wahlberg will star in Transformers 4, The Hollywood Reporter confirms. "Mark is awesome," Bay said. "We had a blast working on Pain and Gain and I'm so fired up to be back working with him. An actor of his caliber is the perfect guy to re-invigorate the franchise and carry on the Transformers' legacy.” Transformers 4 hits theaters June 27, 2014.

• Legos are getting the Hollywood treatment with the help of some big name talent. Liam Neeson, Will Ferrell, Elizabeth Banks and Morgan Freeman have all joined the cast of Lego: Piece of Resistance, THR confirms. Chris Pratt, Alison Brie, Nick Offerman and Will Arnett are also on board for the 3D animated movie. The movie comes to theaters February 7, 2014.

• Two Steve McQueen biopics are in the works, Ace Showbiz reports.
Brothers Chris Hemsworth and Liam Hemsworth are slated to star in the film Triumph AKA 40 Summers Ago, while Jeremy Renner has signed on to a different untitled Steve McQueen flick.

• Chris Hemsworth will also star in the crime thriller Candy Store, Ace Showbiz reports. The film revolves around an operative who must start over after losing everything.

• One Direction may sing "They Don’t Know About Us," but fans will get a behind-the-scenes look at the world of the powerhouse group in their new movie, AceShowbiz reports. "We are going to do our first-ever movie and it's going to be in 3D and it's coming to cinemas near you on the 30th of August, 2013," Niall Horan said on the band's appearance on Today.

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EU drug regulator OKs Novartis' meningitis B shot

LONDON (AP) — Europe's top drug regulator has recommended approval for the first vaccine against meningitis B, made by Novartis AG.

There are five types of bacterial meningitis. While vaccines exist to protect against the other four, none has previously been licensed for type B meningitis. In Europe, type B is the most common, causing 3,000 to 5,000 cases every year.

Meningitis mainly affects infants and children. It kills about 8 percent of patients and leaves others with lifelong consequences such as brain damage.

In a statement on Friday, Andrin Oswald of Novartis said he is "proud of the major advance" the company has made in developing its vaccine Bexsero. It is aimed at children over two months of age, and Novartis is hoping countries will include the shot among the routine ones for childhood diseases such as measles.

Novartis said the immunization has had side effects such as fever and redness at the injection site.

Recommendations from the European Medicines Agency are usually adopted by the European Commission. Novartis also is seeking to test the vaccine in the U.S.

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Jerry Brown hurdles over sophomore traps








SACRAMENTO — There's a strange atmosphere in Sacramento. It's as if there has just been a gubernatorial election and the incumbent has decisively won another term.

All hail the governor. The people have reaffirmed their confidence in his leadership. His contract has been renewed.

That's only the mind playing tricks, of course.






Gov. Jerry Brown merely won passage of a tax increase — and one that was about the easiest imaginable for voters to swallow. Only the top 1% or so will be nailed with the higher income tax rates. There'll be a tiny sales tax bump. The beneficiaries will be schoolchildren and college kids.

Brown still faces reelection in 2014, assuming he's up to running. He'll be 76. But he just showed he's capable of a month-long sprint.

There's no major opponent on the horizon, none of any kind. There's no rational incentive to challenge someone who seems unbeatable. The left wouldn't dare. Brown occupies the center. The right is moribund.

Here's the lofty perch on which the Democrat currently rests: He's the most politically fit California governor at this stage of his tenure since Earl Warren back in World War II. By this stage, I mean following the second year of his reign.

I'd say "most powerful" except that all California governors possess phenomenal power. Some use it better than others. We'll see how Brown uses his in the future.

But for now, he's about the only governor in the last half-century to have escaped the sophomore jinx that has plagued his predecessors.

Go back to his father, Gov. Pat Brown. He was elected by a landslide in 1958. But in his sophomore year, 1960, Brown was dubbed "a tower of jelly" for trying to save notorious "Red Light Bandit" Caryl Chessman from the gas chamber — at son Jerry's pleading. At that summer's Democratic National Convention in L.A., Pat Brown was tagged a "bumbler" for failing to control California's splintered delegation.

His job ratings tumbled. The derisive monikers stuck throughout his career, even though Brown became a great governor.

Ronald Reagan and Jerry Brown — the 1970s version — became afflicted with Potomac fever in their second years as governor, running lamely for president. Reagan recovered; Brown never fully did.

Gov. Pete Wilson suffered a horrendous second year. He meddled awkwardly in Republican legislative primaries and lost. He became bogged down in a summer-long budget quagmire. He sponsored a welfare/budget "reform" initiative that voters rejected. His job approval fell into the low 30s.

Gov. Gray Davis began stumbling down the path to eventual recall in his sophomore year by ducking as the power pirates profited and California fell into an energy crisis. He also was bullied by liberal legislators into spending temporary revenue on permanent programs, leading to huge deficits.

Gov. Arnold Schwarzenegger was a colossal sophomore failure. He called a costly special election for his divisive, clumsily written "reform" package that voters soundly rejected. His approval ratings plummeted.

Contrast all that with Jerry Brown's year. He just bolstered his governorship by finessing rare voter approval of a riskily sought tax increase. At last count, Proposition 30 was ahead by a surprising 9.4 percentage points.

Brown's job approval rating among voters, according to a USC Dornsife/Los Angeles Times post-election poll, is a respectable 49%. And 54% of people under 30 approve of the old guy.

His future is on the upswing. He's not even facing lame-duck syndrome, as he would be if he truly had been reelected to another term. And he should benefit from new supermajority Democratic control of both legislative houses.

Brown is in an extraordinary position to perform great deeds.

This governor doesn't ordinarily like to talk about agendas — he's basically a single-focus type — but he did mention five priorities at a post-election news conference.






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Israel Steps Up Aerial Strikes in Gaza


Tyler Hicks/The New York Times


A man injured by bombing in the Zaitoun neighborhood of Gaza City on Saturday that also killed one person.







GAZA CITY — Israel broadened its assault on the Gaza Strip on Saturday from mostly military targets to centers of government infrastructure, obliterating the four-story headquarters of the Hamas prime minister with a barrage of five bombs before dawn.




The attack, one of several on government installations, came a day after the prime minister, Ismail Haniya, hosted his Egyptian counterpart in that very building, a sign of Hamas’s new legitimacy in a radically redrawn Arab world. That stature was underscored Saturday by a visit to Gaza from the Tunisian foreign minister and the rapid convergence in Cairo of two Hamas allies, the prime minister of Turkey and the crown prince of Qatar, for talks with the Egyptian president and the chairman of Hamas on a possible cease-fire.


But as the fighting ended its fourth day, with Israel continuing preparations for a ground invasion, the conflict showed no sign of abating. Gaza militants again fired long-range missiles at Tel Aviv, among nearly 60 that soared into Israel on Saturday. Israel said it hit more than 200 targets overnight in Gaza, and continued with afternoon strikes on the home of a Hamas commander and on a motorcycle-riding militant.


The White House reiterated its strong support for Israel, with Ben Rhodes, the deputy national security adviser, describing rocket fire from Gaza as “the precipitating factor for the conflict.”


“We believe Israel has a right to defend itself, and they’ll make their own decisions about the tactics that they use in that regard,” Mr. Rhodes told reporters on Air Force One en route to Asia.


Hamas health officials said 45 Palestinians had been killed and 385 wounded since Wednesday’s escalation in the cross-border battle. In Israel, 3 Israeli civilians have died and 63 have been injured. Four soldiers were also wounded on Saturday.


Two rockets were fired at Tel Aviv on Saturday. One landed harmlessly, probably at sea. The other was intercepted by the Iron Dome defense system in the sky above the city. An Iron Dome antimissile battery had been hastily deployed near the city on Saturday in response to the threat of longer-range rockets.


Since Wednesday, Iron Dome has knocked 245 rockets out of the sky, the military said, while 500 have struck Israel. The American-financed system is designed to intercept only rockets streaking toward towns and cities and to ignore those likely to strike open ground.


There have been failures — on Saturday a rocket crashed into an apartment block in the southern port city of Ashdod, injuring five people — but officials have put its success rate at 90 percent.


Analysts said there is no clear end to the conflict in sight, since Israel neither wants to re-engage in Gaza nor to eliminate Hamas and leave the territory to the chaos of more militant factions.


“Ultimately,” said Efraim Halevy, a former chief of Israel’s intelligence service, “both sides want Hamas to remain in control, strange as it sounds.”


But Mkhaimar Abusada, a political science professor at Al Azhar University here, cautioned that “there is no military solution to the Gaza problem.”


“There has to be a political settlement at the end of this,” he said. “Without that, this conflict is just going to go on and on.”


President Mohamed Morsi of Egypt said late Saturday night that “there could be a cease-fire soon,” after he and other members of his government spent the day in meetings with the Turkish premier, the Qatari prince, the political leaders of Hamas and other Gaza factions. But Mark Regev, a spokesman for Prime Minister Benjamin Netanyahu of Israel, denied reports that a truce was imminent.


It was unclear whether the deal under discussion would solely suspend the fighting or include other issues. Hamas — which won elections in Gaza in 2006 and took full control in 2007 but is considered a terrorist organization by Israel and the United States — wants to turn its Rafah crossing with Egypt into a free-trade zone and seeks Israel’s withdrawal from the 1,000-foot buffer it patrols on Gaza’s northern and eastern borders.


Mr. Rhodes said the Turkish and Egyptian leaders “have the ability to play a constructive role in engaging Hamas and encouraging a process of de-escalation.”


Mr. Netanyahu, for his part, spoke Saturday with the leaders of Britain, Germany, Italy, Greece, Poland, Portugal, Bulgaria and the Czech Republic, according to a statement from his office.


Jodi Rudoren reported from Gaza City, and Isabel Kershner from Jerusalem. Reporting was contributed by Fares Akram and Tyler Hicks from the Gaza Strip, Carol Sutherland and Iritz Pazner Garshowitz from Jerusalem, and David D. Kirkpatrick and Mayy El Sheikh from Cairo.



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Google Considering Wireless Network [REPORT]
















Google is looking to cut out the middleman for its Android mobile devices and begin offering wireless service itself, according to a report.


The search giant met with reps from Dish Network to partner on a wireless service “that would rival” wireless networks like AT&T and Verizon, according to The Wall Street Journal, which cited “people familiar with the discussions.” The talks, however, could amount to nothing, the article notes.













[More from Mashable: Google Updates Blogger Mobile Apps to Version 2.0]


Dish bought wireless spectrum in 2008 that it plans to build out into such a network. The company has met with other, unnamed companies aside from Google, according to the report. In an interview this week, Dish Chairman Charlie Ergen said potential partners include companies “who would like to be in the industry” and don’t offer wireless service. He did not name Google or any other of the companies. Despite the talk, there’s speculation that AT&T might partner with Dish on the spectrum offering.


Google bid on wireless spectrum in 2008, but lost to Verizon and AT&T. Google also took a $ 500 million stake in mobile broadband firm Clearwire, which it sold this year for $ 66.5 million.


[More from Mashable: Google Launches Mobile Game You Play in Real Life]


Despite being shut out of wireless for now, Google is offering wired broadband service in Kansas City. The company also diversified into the wireless handset business last year with its $ 12.5 billion purchase of Motorola.


Bonus Gallery: Hands-On: Verizon’s Droid DNA Wows With High-Def Display


Verizon’s Droid DNA


Click here to view this gallery.


This story originally published on Mashable here.


Wireless News Headlines – Yahoo! News



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Sarah Michelle Gellar Names Son Rocky




Celebrity Baby Blog





11/17/2012 at 07:00 PM ET



Sarah Michelle Gellar and Freddie Prinze, Jr. Welcome Son Rocky James
Claire Greenway/Getty


Update: The couple have named their son Rocky James Prinze, a source close to the family confirms to PEOPLE.


Originally posted Sept. 24: Hello, little Prinze.


Sarah Michelle Gellar ”had a baby boy last week in Los Angeles,” her rep tells PEOPLE.


She and husband Freddie Prinze, Jr. “are thrilled to announce” the news, the rep confirms to Access Hollywood, adding that ”mother and baby are doing great.”


The newborn joins the couple’s daughter Charlotte Grace at home.


Their 3-year-old, who was spotted out with a still-pregnant Gellar last Tuesday, “is very excited to be a big sister,” the rep adds.

“They are thrilled that Charlotte [has] a little brother,” a source close to the couple told PEOPLE in July.


“They love their little girl more than anything in the world and know that love will only multiply.”


Gellar, 35, and Prinze, 36, were married in September 2002.


– Sarah Michaud with reporting by Charlotte Triggs


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EU drug regulator OKs Novartis' meningitis B shot

LONDON (AP) — Europe's top drug regulator has recommended approval for the first vaccine against meningitis B, made by Novartis AG.

There are five types of bacterial meningitis. While vaccines exist to protect against the other four, none has previously been licensed for type B meningitis. In Europe, type B is the most common, causing 3,000 to 5,000 cases every year.

Meningitis mainly affects infants and children. It kills about 8 percent of patients and leaves others with lifelong consequences such as brain damage.

In a statement on Friday, Andrin Oswald of Novartis said he is "proud of the major advance" the company has made in developing its vaccine Bexsero. It is aimed at children over two months of age, and Novartis is hoping countries will include the shot among the routine ones for childhood diseases such as measles.

Novartis said the immunization has had side effects such as fever and redness at the injection site.

Recommendations from the European Medicines Agency are usually adopted by the European Commission. Novartis also is seeking to test the vaccine in the U.S.

Read More..